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Cephalexin Capsules, USP



DESCRIPTION


CLINICAL PHARMACOLOGY


Human Pharmacology


Microbiology

   MIC (mcg/mL)        Interpretation    
≤8 Susceptible (S)
16 Intermediate (I)
≥32 Resistant (R)
         Microorganism       MIC (mcg/mL)    
               E. coli                                     ATCC 25922     4-16
             S. aureus                                 ATCC 29213    0.12-0.5
   Zone Diameter (mm)       Interpretation    
≥18 Susceptible (S)   
15-17 Intermediate (I)   
≤14 Resistant (R)    
           Microorganism       Zone Diameter (mm)   
              E. coli                                  ATCC 25922   15-21
              S. aureus                             ATCC 25923    29-37

INDICATIONS AND USAGE


CONTRAINDICATIONS


WARNINGS


PRECAUTIONS


General


Information for Patients


Drug Interactions


Drug/Laboratory Test Interactions


Carcinogenesis, Mutagenesis, Impairment of Fertility


Pregnancy


Teratogenic Effects


Nursing Mothers


Pediatric Use


Geriatric Use


ADVERSE REACTIONS


OVERDOSAGE


DOSAGE AND ADMINISTRATION


HOW SUPPLIED


REFERENCES

  • National Committee for Clinical Laboratory Standards. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria that Grow Aerobically — Fourth Edition. Approved Standard NCCLS Document M7-A4, Vol. 17, No. 2, NCCLS, Wayne, PA, January, 1997.
  • National Committee for Clinical Laboratory Standards. Performance Standards for Antimicrobial Disk Susceptibility Tests — Sixth Edition. Approved Standard NCCLS Document M2-A6, Vol. 17, No. 1, NCCLS, Wayne, PA, January, 1997.
  • National Committee for Clinical Laboratory Standards. Performance Standards for Antimicrobial Susceptibility Testing — Eighth Informational Supplement. Approved Standard NCCLS Document M100-S8, Vol. 18, No. 1, NCCLS, Wayne, PA, January, 1998.